TagsOrthopedics 
The Role of Matrix Metalloproteases in Tendinopathy and Its Clinical Implications

Tendinopathies are generally referred to as conditions including chronic pain and rupture in tendons. Since inflammatory cells are usually absent in the lesion, tendinopathy has long been recognised as a degenerative condition. Accordingly, anti-inf...

Aug 20, 2024
The Puzzling Roles of Substance P in the Pathogenesis of Tendinopathy

Tendinopathy is a common chronic degenerative musculoskeletal condition affecting various body parts, including the Achilles, patellar, rotator cuff, and forearm extensor tendons. The incidence of tendinopathy continues to rise due to an increase in...

Oct 26, 2023
Re-engineering Degenerated Intervertebral Disc with Stem Cell-based Therapy

Discogenic low back pain (LBP) is a common clinical problem that more than 80% of adults would experience at some point in their lifetime. In addition to pain, discogenic LBP substantially worsens the functionality and quality of life of patients an...

Oct 26, 2023
Drink It Or Leave It? A Review on the Association between Coffee Consumption and Bone Health

Drink It Or Leave It? A Review on the Association between Coffee Consumption and Bone Health Coffee is one of the most commonly consumed beverage worldwide. Having a coffee break is relaxing, whereas coffee consumption has been reported to have pote...

Mar 18, 2022
The Therapeutic Potential of Alpha-2-Macroglobulin in Controlling Osteoarthritis

The Therapeutic Potential of Alpha-2-Macroglobulin in Controlling Osteoarthritis Osteoarthritis (OA) is an aging-related chronic degenerative disease characterised by the degradation of chondrocyte extracellular matrix. The disease is one of the mos...

Dec 20, 2021
The Pathophysiological Significance of Neuronal Regulation in Development of Tendinosis

The Pathophysiological Significance of Neuronal Regulation in Development of Tendinosis Tendinopathy is a clinical condition characterised by pain and swelling in and around tendons, whereas tendinosis is a chronic, degenerative condition with objec...

Mar 16, 2021
The Potential Risk of Intervertebral Disc Degeneration upon Microgravity Exposure

The Potential Risk of Intervertebral Disc Degeneration upon Microgravity Exposure Low back pain (LBP) is one of the disorders with highest health burden globally. The disorder causes limitations in activity and work capacity leading to considerable ...

Sep 16, 2020