Precision oncology (PO), defined as molecular profiling of tumours to identify targetable alteration 1 . The approach has shifted away from non-specific cytotoxic treatment to a more individualised cancer treatment. The advancement in diagnostic tec...
Multiple myeloma is a clonal plasma cell proliferative disorder that is often diagnosed in individuals aged 65 to 74 years 1 . Notably, the treatment landscape of MM has evolved over the last few years with availability of newer agents and combinati...
Multiple myeloma (MM) is a clonal plasma cell disorder characterised by excess production of monoclonal immunoglobulins and light chains that can ultimately lead to specific end-organ damage 1 . Notably, MM is the second most common haematologic mal...
Prostate cancer (PCa) is a complex disease that affects millions of males, globally. It is the 3rd most common cancer in males and the 4th leading cause of male cancer-related deaths in Hong Kong1. The aetiology of PCa is believed to be related to s...
Hepatocellular carcinoma (HCC) is ranked as the sixth most common cancer worldwide and its incidence has been progressively increasing. HCC is also the third most common cause of cancer-related death, with a 5-year survival rate of just 3% 1 . Inter...
TARGRETIN™ (bexarotene) MAIN LIFE HK Reg. No. HK-68294 (04 Jul, 2024) Composition: 1 Targretin™ (bexarotene) is a member of a subclass of retinoids that selectively activate retinoid X receptors (RXRs). Targretin™ is available in c...
Multiple myeloma (MM) is a haematologic malignancy characterised by abnormal clonal plasma cells in the bone marrow with a potential for uncontrolled growth causing destruction, osseous lesion, acute kidney injury (AKI), anaemia, and hypercalcaemia....
Tumour protein 53 (TP53) gene is located on the chromosome 17 that encodes for the p53 protein, which is a tumour suppressor protein with 393 amino acid responsible for regulating cellular stress 1 . Notably, TP53 can be inactivated directly due to ...
Paradigm Shift in Management of Unresectable Hepatocellular Carcinoma (uHCC) In Hong Kong, liver cancer is the fifth most common cancer (with 1,771 new cases of liver cancer reported in 2021) and the third most common cause of cancer-related deaths ...
Early Insight to the Dyslipidaemia Pandemic Dyslipidaemia is defined as lipid imbalance affecting the low high-density lipoprotein cholesterol (HDL-C), elevated triglyceride (TG), high low-density lipoprotein cholesterol (LDL-C) and elevated total c...
EXKIVITY (mobocertinib) TAKEDA Indications: EXKIVITY is indicated for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, ...
