Renal cell carcinomas (RCCs) are the most common type of kidney cancer in adults, particularly in adult males. Given that a substantial portion of RCCs are diagnosed at advanced stages, disease-specific survival is a clinical concern. Moreover, RCC also triggers significant psychological distress, impairing the overall quality of life of the patients. In the Feature Story, the pathophysiology and clinical management of RCC are reviewed. Essentially, the recent developments in diagnostic techniques and therapeutics against RCC are highlighted.
In the current Focus section, Dr. Lynden Christian of the National Hospital Service (NHS), United Kingdom (UK), is invited to share his insights into rosacea. Rosacea is a common chronic inflammatory disease that presents with recurrent flushing, erythema, telangiectasia, papules, and/or pustules affecting the centrofacial region. Besides skin symptoms, the disease burden of rosacea is significant and extensive, which potentially induces a wide range of systemic diseases and psychosocial impacts. Dr. Christian uncovers the real clinical challenges faced in diagnosing, particularly in dark-skinned individuals, and the holistic treatment approach to countering rosacea.
The thematic topics aside, the updates in the management of long-chain amyloidosis in local clinical settings and the controversies on parenteral nutrition therapy are featured in the Industry Updates. Moreover, the pathophysiology of early-onset dementias and the technology for resolving infertility are discussed in the Epoch section. Remarkably, updates in the pharmacological management of respiratory syncytial virus (RSV) infection, dyslipidaemia, and acne scarring are included in the current issue as well. Last but not least, the roles of semaglutide in managing various metabolic disorders are discussed.
Hope you enjoy this issue!
Dr. Roy Yuen-chi Lau
PhD, DBA, MPH, MMedSc, MA, BSc,
FRSPH, MIET, MRSC, MSB, CBiol, CSci, MRACI CChem
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