TagsGastroenterology 
REZDIFFRA

REZDIFFRA (resmetirom) MADRIGAL PHARMCEUTICALS Composition: 4 60 mg, 80 mg, 100 mg Indications: 4 REZDIFFRA is indicated in conjunction with diet and exercise for the treatment of non- alcoholic steatohepatitis (NASH) with moderate to advanced liver...

Apr 19, 2024
Exploring the Transformative Advances in Management of Crohn’s Disease

Crohn's disease (CD), similar to ulcerative colitis, causes digestive disorders and both of them are classified as inflammatory bowel diseases (IBD) 1 . According to epidemiological data, the incidence of CD has been rising in Hong Kong over the...

Apr 19, 2024
The Ever-Changing Landscape of Unresectable Hepatocellular Carcinoma

Paradigm Shift in Management of Unresectable Hepatocellular Carcinoma (uHCC) In Hong Kong, liver cancer is the fifth most common cancer (with 1,771 new cases of liver cancer reported in 2021) and the third most common cause of cancer-related deaths ...

Apr 18, 2024
Don’t Just Blame Ageing for Skin Wrinkle, Blame the Skin Microbiomes

Human skin aging is a natural and intrinsic process that involves shift of endogenous processes combined with external environmental factors such as exposure to the ultraviolet (UV) and pollution. These factors induce physiological changes which may...

Feb 6, 2024
Energising the Well-being of Disease-related Malnourished Patients – The Clinical Issues of Parenteral Nutrition

Patients with acute or critical illnesses are susceptible to developing malnutrition, either as a direct result of the disease or due to treatment adverse effects (ADs)1. While disease-related malnutrition (DRM) is associated with various adverse ou...

Feb 6, 2024
The True Powers of Vitamin B12 in Ulcerative Colitis

Many processes of tissue injury and repair in adult organs proceed through a transient dedifferentiation to a more developmentally primitive state. Recent studies have suggested vitamin B12 administration during an injury may promote cell plasticity...

Dec 18, 2023
Biological Changes Happen Long Before IBD Becomes Symptomatic

Inflammatory bowel disease (IBD) has a higher prevalence in developed western countries than in East Asia, with about 120 to 200 cases per 100,000 for ulcerative colitis (UC) and 50 to 200 cases per 100,000 for Crohn¡¦s Disease (CD) in ...

Dec 18, 2023
Pay Attention to Cardiovascular Risks in Patients with Autoimmune Disorders

Autoimmune disorders, such as rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus, and type 1 diabetes, were found to be linked with increased CV risks, with risk dependent on the types of autoimmune disorders. In a population-b...

Jun 13, 2023
The New Age of Colorectal Cancer

Existing Knowledge on Colorectal Cancer Colorectal cancer (CRC) is the third most common type of cancer and second most common cause of cancer-related deaths globally 1 . There were over 1.9 million new cases of CRC globally in 2020 with medium to h...

Jun 13, 2023
Keep the Gut Out of Mischief The Advancement in Diagnosis for Colorectal Cancer

Where Are We in the Prevention of CRC? Ageing and male gender are common risk factors for CRC. In addition, a positive family history, a history of familial adenomatous polyposis, occurrence of Lynch syndrome, development of colonic polyp, and ulcer...

Dec 20, 2021
Exploring Chemotherapy-associated Cognitive Impairment in Colorectal Cancer

Exploring Chemotherapy-associated Cognitive Impairment in Colorectal Cancer Chemotherapy, which is commonplace in treating a plethora of cancers, has seen increasing concerns over its possible role in inducing cognitive impairment 1 . In breast canc...

Dec 20, 2021
Combating Clostridioides Difficile Infection by Microbiota-based Therapy

Combating Clostridioides Difficile Infection by Microbiota-based Therapy Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated diarrhoea and is associated with significant morbidity and mortality. In Hong Kong, the e...

Dec 20, 2021