Chronic lymphocytic leukaemia (CLL) is a chronic lymphoproliferative disorder characterised by proliferation of monoclonal mature B-cells in peripheral blood, bone marrow, and secondary lymphoid tissues, such as spleen and lymph nodes 1 . The incide...

The Unmet Need in Preventive Therapy for Migraine The pharmacotherapy of migraine involves the treatment of acute headaches and prophylaxis for preventing headaches 3 . Among the key goals of migraine preventive treatment, Prof. McAllister emphasise...

Understanding the molecular mechanisms of different diseases allows us to develop novel medicines. Yet, developing a brand-new drug is relatively costly and laborious, especially for treating rare diseases. Drug repurposing has been progressively gr...

Antibiotic is extensively used in clinical practices for treating bacterial infections. Yet, antibiotic resistance is also a serious global health concern and resistant bacteria have posed tremendous threat to global health in 21 st century. A recen...

Originally indicated for preventing organ rejection in patients receiving organ transplants, rapamycin is now being explored for its potential to intervene with the aging process and extend lifespan. A recent study showed that topical application of...

Recent Development in Pharmacological Treatment for Cannabis Use Disorder Cannabis is one of the most commonly used illicit drugs that an estimate of 13.9% of the general population older than 12 reported past-year use in the United States in 2016, ...

In a nationwide study of patients with chronic viral hepatitis in Sweden, the long-term effects of low-dose (≤160 mg) aspirin on incident hepatocellular carcinoma (HCC), liver-related mortality, and gastrointestinal bleeding were investigated. 50...