Cytokine release syndrome (CRS) is a life-threatening acute systemic inflammation caused by the over-reacted network of cytokines including interleukin (IL) -1, IL-6, IL18, etc. Among these, IL-6 regulating vascular homeostasis and inflammation is o...
The increasing prevalence of allergic diseases worldwide, especially in developed countries, has prompted scientists to investigate the driving force behind it. Although the alterations and characteristics of microbiomes have been studied in relatio...
Autoimmune disorders, such as rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus, and type 1 diabetes, were found to be linked with increased CV risks, with risk dependent on the types of autoimmune disorders. In a population-b...
The POEMS syndrome is a rare plasma cell disorder involving pathological changes of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes. The diagnostic and therapeutic management of the disease is clinically challenging. Given ...
Herpes zoster (HZ), also known as shingles, is caused by the reactivation of Varicella-zoster virus (VZV) that commonly leads to chickenpox. Normally, VZV remains dormant in the dorsal root ganglia or the sensory ganglia of the cranial nerve after a...
People at Increased Risk of Rheumatoid Arthritis Patients with RA often experience a reduced quality of life in several domains, such as physical health, level of independence, environment, and personal beliefs, compared with the healthy population ...
Chronic rhinosinusitis (CRS) describes a heterogeneous spectrum of persistent inflammatory diseases affecting the paranasal sinuses. In particular, CRS with nasal polyps (CRSwNP) represents the subtype of CRS considered to have a clinically more sev...
With growing awareness on personal and household hygiene against infections, the increased use of cleaning products may ring an alarm. A Canadian longitudinal study revealed that frequent use of cleaning products in homes of infants may increase the...
