Autoimmune disorders, such as rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus, and type 1 diabetes, were found to be linked with increased CV risks, with risk dependent on the types of autoimmune disorders. In a population-b...
The POEMS syndrome is a rare plasma cell disorder involving pathological changes of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes. The diagnostic and therapeutic management of the disease is clinically challenging. Given ...
Current Diagnostic Challenges in PD In contrast to the beliefs in the old days, clinical diagnosis of PD is difficult in reality. A meta-analysis reported that the pooled diagnostic accuracy of PD was 80.6% 1 . Prof. Poewe highlighted that a substan...
The Unmet Need in Preventive Therapy for Migraine The pharmacotherapy of migraine involves the treatment of acute headaches and prophylaxis for preventing headaches 3 . Among the key goals of migraine preventive treatment, Prof. McAllister emphasise...
Treatment Goals and Potential Therapies in PD Prof. Fox addressed that the primary goals of the management of early PD are to control motor symptoms, to prevent both motor and non-motor complications, and to modify progression, whereas those for adv...
Dementia is one of the most prevalent age-related diseases worldwide and may impair the ability of the old people to maintain social connectedness. The results of a 2011-2014 Chinese Longitudinal Healthy Longevity Survey comprising 5716 participants...
Multiple health benefits of cocoa flavanols have been extensively investigated in various clinical studies. It is believed that cocoa flavanols can protect against cognitive ageing. Recent research has shown that cocoa flavanols may improve cerebral...
The webinar on Clinical Approach to Dementia Screening was successfully held on 28th October 2020. Dementia is a progressive brain disorder with the decline in cognitive and intellectual functions such as memory, comprehension and learning capacity...
Handwriting abnormalities, such as difficulty in signing and micrographia, are motor deficits frequently encountered by Parkinson Disease (PD) patients which may deteriorate their quality of life. A recent trial examining the effectiveness of a 4-we...
Addiction is generally characterised by neurotransmitter changes in the mesocorticolimbic system of our brain. While our reliance on internet and smartphones continues to grow, existing research on such technological addiction is still limited. In a...
Defining the Concept of Vascular Cognitive Impairment (VCI) Introduced just around two decades ago, VCI is a fairly recent concept that refers to the full spectrum of cognitive impairment associated with cerebrovascular diseases, ranging from subjec...
The B Vitamins The B vitamins are a collection of eight water-soluble, chemically very heterogeneous organic compounds. They function as coenzymes for enzymatic reactions in different biological systems. Their collective effects include energy produ...
