Researchers have identified a promising experimental drug that could treat heart failure with preserved ejection fraction (HFpEF), the most common type of heart failure for which no therapy currently reduces mortality. In animal studies, the drug RB...

Obesity is linked to accelerated cardiovascular aging, but the role of different fat distribution patterns remains unclear. Using machine learning and whole-body imaging in 21,241 participants, researchers predicted cardiovascular age and analyzed b...

In a groundbreaking study from Osaka University, researchers report that tricaparin, a common dietary supplement, has led to remarkable clinical improvements in two patients with triglyceride deposit cardiomyovasculopathy (TGCV), a rare form of coro...

The disease burden of cardiovascular diseases (CVDs) is significant, accounting for approximately 400 million disability-adjusted life years (DALYs) in 2019 globally. Despite multinational and multipronged cardiovascular preventative strategies, the...

Autoimmune disorders, such as rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus, and type 1 diabetes, were found to be linked with increased CV risks, with risk dependent on the types of autoimmune disorders. In a population-b...

The POEMS syndrome is a rare plasma cell disorder involving pathological changes of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes. The diagnostic and therapeutic management of the disease is clinically challenging. Given ...