Rare diseases typically have a prevalence below 0.05% and constitute around 10,000 diseases, cumulatively affecting over 5% of the global population. Although there is a large unmet need in treatment, the recent advent of gene therapy is beginning t...

Existing Knowledge on Colorectal Cancer Colorectal cancer (CRC) is the third most common type of cancer and second most common cause of cancer-related deaths globally 1 . There were over 1.9 million new cases of CRC globally in 2020 with medium to h...