Novel Approach to Eradicate Osteosarcoma Cells and Promote Osteoblast Proliferation¹

In a recent study, curcumin which is the active constituent for turmeric, is encapsulated in a liposome, and incorporated onto a 3D printed (3DP) calcium phosphate (CaP) scaffold, providing new tissue ingrowth. Liposomal curcumin released from the 3DP scaffold showed significant cytotoxicity toward in vitro osteosarcoma cells, whereas promoted osteoblast cell viability and proliferation. This novel approach incorporating modern 3D printing technology with safe, effective use of alternative medicine, offers opportunities to treat bone defects after tumour resection.

Reference

1. Sarkar N, et al. ACS Appl Mater Interfaces 2019;11:17184-17192.