TagsPharmacology 
A New Cornerstone in AL Amyloidosis Treatment

AL Amyloidosis: A Rare but Multifaceted Disease Light chain (AL) amyloidosis is a rare multi-systemic, incurable protein misfolding disorder characterised by plasma cell dyscrasia and abnormal clonal plasma cell proliferation 1 . Immunoglobulin secr...

Feb 6, 2024
Rejuvenating Effects of Aging: Fact or Fiction?

The New Paradigm Shift in Aging Aging is a process of chronic, normal culmination of the loss of specific regenerative and bioprotective mechanism that occurs over a period. In addition, at cellular level, primary aging-related mechanisms occurs as ...

Oct 26, 2023
The Unseen Challenges of Drug-Resistant Epilepsy

The Burden and Unmet Needs in Epileptic Sufferers EEpilepsy is one of the most common neurological conditions, with a prevalence of 0.5% to 1% 1 . It is considered a chronic brain disorder that affects people of all ages without geographical, social...

Oct 26, 2023
Combined Forces of Revascularisation and Optimal Medical Therapy in Conquering Chronic Coronary Syndrome

Ischaemic heart disease (IHD) has traditionally been categorised into acute coronary syndrome (ACS) and coronary artery disease (CAD) 1 . With a better understanding of Cardiology and therapeutic advancement, the European Society of Cardiology (ESC)...

Oct 26, 2023
An Update on the Role of SGLT-2 Inhibitor in the KDIGO Guideline on the Management of CKD

The Burden of Chronic Kidney Disease Chronic kidney disease (CKD) is one of the most prominent causes of death and suffering in the 21 st century. The number of patients affected by CKD has substantially increased with an estimate of 843.6 million i...

Oct 26, 2023
Euthyrox

Euthyrox ® (levothyroxine sodium) Merck Composition: • Available as tablet containing 25, 50 or 100 µg of levothyroxine sodium Indication: • Euthyrox® 25-200 µg is indicated for the substitution therapy in hypothyroid...

Oct 24, 2023
Kerendia

Kerendia ® ( Finerenone ) 4 Bayer Finerenone is a nonsteroidal mineralocorticoid receptor (MR) antagonist Compositio n : Available as 10mg and 20mg oral tablets Indications : Newly indicated for delaying progressive decline of kidney function ...

Jun 13, 2023
Triplixam

Triplixam ® ( perindopril arginine/indapamide/amlodipine ) 5 Servier Perindopril is an angiotensin converting enzyme inhibitor (ACE inhibitor) Indapamide is a thiazide diuretic Amlodipine is a calcium-channel blocker (CCB) Compositio n : Availa...

Jun 13, 2023
Vyepti

Vyepti ® ( Eptinezumab ) 6-7 Lundbeck Eptinezumab is a recombinant humanized monoclonal antibody that selectively inhibits calcitonin generelated peptide (CGRP) Compositio n : Available as a 100 mg/1mL concentrated solution for infusion Indica...

Jun 13, 2023
Always-available Psychotherapy for Depression and Anxiety by AI

Shortage of healthcare manpower is a common issue faced by many societies, including mental health professionals. It affects the access to relevant services and taxes on the cost for utilization as a result. Digital mental health applications are th...

Jun 13, 2023
Cancer Cells Use Uridine-derived Ribose as Fuel when Starved

Pancreatic ductal adenocarcinoma (PDA) is called a silent killer, as it is often discovered late and has a high mortality rate. Its treatment-resistant and aggressive nature can be attributed to the tumour microenvironment, low vascularity, and meta...

Jun 13, 2023
The Promising Fixed-duration Oral Regimen for Older and Unfit Patients with Chronic Lymphocytic Leukaemia

Chronic lymphocytic leukaemia (CLL) is a chronic lymphoproliferative disorder characterised by proliferation of monoclonal mature B-cells in peripheral blood, bone marrow, and secondary lymphoid tissues, such as spleen and lymph nodes 1 . The incide...

Jun 13, 2023