TagsInfectious Diseases 
Future Zoonotic Outbreak Prevention Framework

Humanity just made it through the challenges posed by the COVID-19 pandemic. In the past 20 years, our society has seen multiple notable human outbreaks of infectious diseases, including the avian influenza, zika virus and of course severe acute res...

Oct 24, 2023
Mycobacterium tuberculosis disease amplifies HIV-1-specific antibody response

Tuberculosis (TB) is caused by the infection of mycobacterium tuberculosis (Mtb). In developing countries, co-infection of Mtb and HIV are common, as HIV could exacerbate TB. Nevertheless, the reverse impact of Mtb infection on HIV development has r...

Aug 11, 2023
Dengue Fever: Ever Changing Paradigms of Communicable Diseases

Re-Emergence of the Past into the Present The earliest outbreak of dengue was reported in Jakarta during the year 1779, Indonesia and the virus causing the disease was identified during the early 20 th century 5 . Dengue has since become a global pr...

Aug 11, 2023
Shingles – Can We Avoid the Ambush?

Herpes zoster (HZ), also known as shingles, is caused by the reactivation of Varicella-zoster virus (VZV) that commonly leads to chickenpox. Normally, VZV remains dormant in the dorsal root ganglia or the sensory ganglia of the cranial nerve after a...

Jun 13, 2023
Strategies for Antibiotic Selection for Empirical Therapy of Severe Infections

The Importance of Timely Treatment In local clinical settings, Enterobacteriaceae, including both E. coli and K. pneumoniae , exhibiting resistance to cephalosporins (extended-spectrum β-lactamase [ESBL] phenotype) and carbapenems, P. aeruginos...

Sep 20, 2021
Consensus Recommendations on COVID-19 Vaccination

Consensus Recommendations on COVID-19 Vaccination in Adult Patients with Autoimmune Rheumatic Diseases by the HKSR Clinical opinions generally advocate that COVID-19 vaccination is a critical measure to contain the current pandemic. Notably, patient...

Sep 17, 2021
Higher Risk for Severe COVID-19 Outcomes Associated with Physical Inactivity

Different guidelines call for all adults to engage in at least 150 minutes/week of moderate to vigorous physical activity. It is well-known that regular physical activity reduces the risk of systemic inflammation, which is a major contributor to lun...

Jul 21, 2021
A Review on the Impacts of Work from Home Arrangement on Health and Business Operation during COVID-19 Pandemic

A Review on the Impacts of Work from Home Arrangement on Health and Business Operation during COVID-19 Pandemic The development in information technologies facilitates digitalisation and a growing globalising endeavour leading to a significant impro...

Mar 16, 2021
With Vaccination, Can We Resist the Evolutionary Force of Viruses?

With Vaccination , Can We Resist the Evolutionary Force of Viruses ? COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has been a challenging pandemic in the 21 st century 1 . The highly pathogenic SARS-CoV-2 has ...

Mar 16, 2021
Novel Antiviral Mechanism Targeting Pressurised DNA State in Herpesvirus

Novel Antiviral Mechanism Targeting Pressurised DNA State in Herpesvirus Herpes simplex virus (HSV) is a highly contagious viral infection prevalent across the world. With HSV-1 and HSV-2 being the most common types, approximately 90% of people worl...

Mar 16, 2021
Ureaplasma Urealyticum/ Ureaplasma Parvum (UU/UP): An Emerging Resistant Pathogen with Potential Severe Consequences

Is It a True Pathogen? Ureaplasma can live in the mucosa of urogenital tract of healthy adults without causing any symptoms. It was found that up to 80% of sexually mature female have Ureaplasma spp. in their genital tract 2 . It was found in 5 to 1...

Mar 16, 2021
WHO: Remdesivir, Hydroxychloroquine, Lopinavir, and Interferon Regimens Do Not Reduce Mortality Caused by Covid-19

World Health Organization (WHO) conducted a large, open-label, randomised-controlled trial involving hospital inpatients to evaluate the effects of remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a on mortality caused by Covid-19. Th...

Dec 16, 2020