The Potential and Challenge of Gene-edited Cellular Therapies The recent advances in genome editing allow precise manipulation of cellular DNA sequences and have raised hopes of curing serious genetic diseases. CRISPR-Cas9 is a specific and efficien...
Nutrition Intervention for Improving Health Outcomes of Cancer Patients Malnutrition is prevalent among cancer patients, whereas up to 70% of patients are at risk. The condition can adversely affect treatment outcomes, quality of life and survival 1...
Over the past 25 years, significant progress has been made in the treatment of multiple myeloma (MM) as reflected by the improved overall survival (OS). However, in relapsed and refractory MM (RRMM), median OS decreases with each extra line of thera...
The Live Symposium on Breast Health Education 2021 Breast cancer is the most common cancer among women both globally and locally, whereas the number of locally diagnosed female breast cancer cases has increased by 4 times from 1993 to 2018. This ind...
Standard Treatment Regimens for NSCLC and the Potential Challenges “Treatment goals vary across NSCLC patients at different stages of the disease. For patients at early and intermediate stages of NSCLC, they are usually treated with curative i...
T he Importance of Achieving Deepest Possible Response and Continuous Therapy While improving long-term survival for patients with MM is desirable, clinical data suggested that complete response (CR) to treatment is associated with survival outcomes...
Uncovering Psychological Burden of Advanced Prostate Cancer Psychological distress is prevalent among patients with advanced PCa as compared to those with localised disease, and the morbidity adversely affects patients’ HRQOL 4 . Essentially, ...
Breast cancer is one of the prevalent malignancies among females in Hong Kong. To investigate the potential impacts of regular screening on disease diagnosis and mortality, a randomised controlled trial recruited 151, 538 women aged 35-64 with no hi...
Breast cancer is one of the life-threatening malignancies among females in Hong Kong. Obesity is recognised as being correlated with poor prognosis in several cancers, including breast cancer. A recent meta-analysis which included 27 studies had dis...
E-cigarettes have become a popular stop tobacco smoking aid in recent years. However, evidence on the effectiveness of e-cigarettes for assisting people to quit tobacco smoking remains controversial. In a Cancer Research UK-funded study, researchers...
Poor Prognosis in Patients with Stage III Non-Small-Cell Lung Cancer (NSCLC) NSCLC, which accounts for 80-85% of all cases of lung cancer, constitute one of the leading causes of mortality worldwide 6,7 . In approximately 30% of patients, the diseas...
Recent Advances in Therapies for Gastrointestinal Stromal Tumour Gastrointestinal stromal tumour (GIST) is the most common mesenchymal tumour of the gastrointestinal (GI) tract, mainly in the stomach and small intestine. GIST constitutes a distinct ...