TagsEndocrinology 
Exkivity

Exkivity® ( mobocertinib ) 1-3 Takeda Mobocertinib is a kinase inhibitor of the epidermal growth factor receptor (EGFR) that selectively inhibits and irreversibly binds to EGFR exon 20 insertion mutations at lower concentrations than Wild type (...

Jun 13, 2023
Kerendia

Kerendia ® ( Finerenone ) 4 Bayer Finerenone is a nonsteroidal mineralocorticoid receptor (MR) antagonist Compositio n : Available as 10mg and 20mg oral tablets Indications : Newly indicated for delaying progressive decline of kidney function ...

Jun 13, 2023
Hyperuricaemia Management in Hong Kong FAST Trial Reveals Non-inferiority

Hyperuricaemia Overview in Hong Kong Hyperuricaemia is defined as the elevated urate acid level in blood ≥ 6.8 mg/dL 2,5 . In Hong Kong, the crude prevalence of gout was 2.9% according to a population study in 2016, which was similar to the rate ...

Jun 21, 2021
Greater Risk of Hyperhomocysteinemia Associated with Age and Folate Deficiency

Hyperhomocysteinemia (HHcy) is well known to be associated with increased risk of different diseases including cardiovascular diseases, diabetes and neurodegenerative diseases. To have a better understanding of pathogenesis of HHcy and evaluate the ...

Apr 28, 2021
Association of Obesity with Poor Breast Cancer Outcome

Breast cancer is one of the life-threatening malignancies among females in Hong Kong. Obesity is recognised as being correlated with poor prognosis in several cancers, including breast cancer. A recent meta-analysis which included 27 studies had dis...

Apr 14, 2021
Make an impact on weight management with semaglutide

The prevalence of overweight and obesity has continued to grow in adults and children more than four times from 1975 to 2016 globally. A second study of an injectable anti-obesity medication, semaglutide, reported to be able to make an impact on wei...

Mar 31, 2021
Double-edged Correlation between Daytime Napping Duration and Metabolism-related Diseases

Daytime napping is a common practice in many countries which is believed to reduce sleep deficits and improve emotional status. However, a recent Chinese study has suggested that daytime napping may be detrimental to our health under certain conditi...

Mar 24, 2021
The Sooner the Better: Timely Control on Hypercholesterolaemia

While the general public are often told that “bad diet” is the culprit of high cholesterol, most of the patients have missed the crunch time to manage it through lifestyle modification until condition gets worse or atherosclerosis and it...

Dec 15, 2020
Cholesterol: Lower is Better. But What is the Best Way to Get There?

Blood lipid disorders have become global health concerns in the 21 st century 1 . In previous guidelines for managing dyslipidaemias, the importance of low-density lipoprotein cholesterol (LDL-C) lowering to prevent atherosclerotic cardiovascular di...

Sep 16, 2020
The Hormonal Change Triggered by E-sport

E-sport competitions are organised in a relatively controllable setting as compared to those of physical sports, while existing research works on physiological and psychological impacts of E-sport are limited. A recent investigation on influencing f...

Jul 1, 2020
The Endocrinology, Diabetes & Metabolism Hong Kong (EDMHK) 2nd Annual Meeting

The Endocrinology, Diabetes & Metabolism Hong Kong (EDMHK) 2 nd Annual Meeting The Endocrinology, Diabetes & Metabolism Hong Kong (EDMHK) 2019 meeting held on 26th – 27th October 2019 was jointly organised by the University of Hong Kon...

Dec 16, 2019
Modulation of Growth Hormone-Insulin-Like Growth Factor (GH-IGF) Axis by Pregnancy-associated Plasma Protein-A2 (PAPP-A2)

Regulation of GH Secretion and GHD Growth hormone deficiency (GHD) is caused either directly by the total or partial absence of growth hormone (GH) or by secretion of abnormal GHs, or indirectly by decreased level of GH-dependent growth factors such...

Dec 16, 2019